Is there any effect of sequential eradication therapy of helicobacter pylori on functional dyspepsia symptom resolution ?

Dyspepsia is one of the most common chronic illness- es of adults and affects up to 40% of the population in the Western world (1). Similarly, dyspepsia affects 28.4% of population in Turkey and a majority of them were taking medications for dyspepsia (2). Functional dyspepsia (FD), a common functional gastrointestinal disorder, is defined by the Rome III criteria as symptoms of epigas- tric pain or discomfort, postprandial fullness, and early satiety within the last 3 months with symptom onset at least 6 months earlier (3). Recent data supports that Heli- cobacter pylori (H. pylori) eradication provides signifi- cant benefits to patients with FD. The Maastricht IV Con- sensus Report recommends it (4). In this regard, we aimed to clarify if sequential therapy has an effect on symptom resolution of FD patients with H. pylori using a validated health quality index.